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Drone frames are very usefull in beekeeping.
Colony rear drones what ever you do. They have strong instincts to get them. It is one of their main purposes in life: To deliver genes...
If you do not give space to draw drone cells, bees do them however here and there. Sometimes they tear down foundations and make drone cells.
I put into langstroth frame medium size foundation. Then bees have 1/3 frame gap for drones. Those frames I put to the hive 2 pieces.
A whole drone frame is too much.
When I inspect hives, I cut a drone zone away, and bees can rear again new drone brood.
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In natural comb hives bees do 25-30% drone combs. I try to keep them under 10%
Bees are very happy when they have drones. I do not believe much to varroa control via drone culling. But I can see from drone brood the varroa level, how severe is amount of mites.
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